The effect of phase formation on biomechanical and biological performance of Li2O-Al2O3-SiO2 glass-ceramics

Lithium aluminum silicate (LAS, Li2O-Al2O3-SiO2) glass-ceramics have been employed in dentistry as substitutes while seldom orthopaedics. This is primarily due to difficulties with balancing the biomechanical and biological performance. study aims investigate effects of SiO2 content thermal treatment on formation Li2SiO3, Li2Si2O5 LiAlSi2O6 LAS glass-ceramics, these crystalline phases The preparation were divided into two stages. In first step, six components (C1, C2, C21, C22, C23 C3) prepared characterized. second CN1, CN2 CN3 principal obtained based C1, C22 C3 evaluated biomechanics biology. With increasing from 65.11% 67.96%, correspondently increased. extension holding time at 850 °C promoted generation expense Li2Si2O5. main phase coupled (dominated by LiAlSi2O6) resulted a high flexural strength 378 ± 29 MPa favorable cell viability 115.21 14.63%. impressive results indicate that this glass-ceramic may be good candidate for orthopaedic applications.